Provitamin D in animal tissues

Phosphorus Compounds in Animal Tissues

The concept that nucleic acids are intimately associated with fundamental cellular processes has gained considerable favor within the last few years. This can undoubtedly be attributed to the researches of Caspersson and his associates. Caspersson, with the aid of ultraviolet spectrophotometry, has been able to measure the nucleic acids in various parts of the cell under a variety of experiment...

Deoxyribosyl compounds in animal tissues.

Several types of deoxyribosyl compounds have been found in the acidsoluble fraction of normal and malignant tissues (l-8). In 1955 Potter and Schlesinger (1) reported the isolation of deoxynucleoside mono-, di-, and triphosphates from extracts of calf thymus. More recently LePage (7) reported the isolation of deoxyadenosine triphosphate from a tumor. Schneider (2), using a microbiological assay...

Drug residues in animal tissues.

Provitamin D3 in tissues and the conversion of cholesterol to 7-dehydrocholesterol in vivo.

The discovery that the absorption bands at 293, 281-5 and 271 m,u. (Heilbron, Kamm & Morton, 1926, 1927) present in fractions obtained in the recrystallization of cholesterol were shown very strongly by ergosterol (Rosenheim & Webster, 1927) focused interest on the latter and culminated in the isolation ofcalciferol (vitamin D2). Some time later it was recognized that 7-dehydrocholesterol was a...

Metabolic activities of vitamin D in animals. IV. Distribution of vitamin D sulfokinase in animal tissues and its isolation.

In the foregoing paper (1), the biogenesis of vitamin D sulfate in animal tissues was reported. Further, the distribution of vitamin D sulfate-forming enzyme in various tissues was studied and the authors have succeeded in isolating vitamin D sulfokinase from rat-liver homogenate. Isotopic investigation of the enzyme activity was also made. Preliminary reports of these findings were already mad...